East San Diego Homes with Mixed Use Subtype

Welcome to East San Diego, a vibrant and diverse community nestled in the heart of California's picturesque San Diego County. Known for its sunny weather, friendly neighborhoods, and rich cultural heritage, East San Diego offers a unique blend of urban convenience and suburban charm. With easy access to major highways and public transportation, residents enjoy seamless connectivity to the bustling downtown area, pristine beaches, and the natural beauty that surrounds this enchanting city.

One of the most exciting features of East San Diego's real estate market is the availability of homes with a mixed-use subtype. These innovative properties seamlessly blend residential and commercial spaces, offering homeowners the opportunity to live, work, and play all in one location. Imagine waking up in your stylish loft, stepping out to your café or boutique on the ground floor, and enjoying the vibrant community just outside your door. This dynamic lifestyle is perfect for entrepreneurs, creatives, and anyone looking to embrace the convenience of modern living.

East San Diego's mixed-use homes are thoughtfully designed to cater to a variety of needs, featuring spacious layouts, contemporary finishes, and eco-friendly elements. Whether you're seeking a cozy studio or a larger family residence with an office space, you'll find options that suit your lifestyle. Plus, with a plethora of local parks, restaurants, and shops nearby, you'll never have to venture far to enjoy everything this charming city has to offer.

Discover the allure of East San Diego and explore the exciting opportunities that await you in the world of mixed-use living. Your perfect home is just around the corner!

Newest East San Diego Homes with Mixed Use Subtype

$3,700,000

260023699SD MLS ⋅ Active Status

We are pleased to present “Stonegate Manor,” a 19-unit multifamily community located in the City Heights neighborhood of San Diego, California.? Located at 3829 Marlborough Avenue, the property offers investors the opportunity to acquire a well-maintained asset with significant infrastructure improvements, upgraded unit interiors, abundant parking, and a highly efficient unit mix.? Built in 1972, the property is situated on an approximately 0.32-acre lot and is comprised entirely of nineteen (19) one-bedroom/one-bathroom units averaging approximately 600 square feet.? Ownership has completed substantial improvements to the property’s major building systems, including a complete electrical rewire and upgraded plumbing systems.? These capital improvements provide a future owner with the benefit of modernized infrastructure while reducing the potential for significant near-term capital expenditures.? All unit kitchens and bathrooms have also been upgraded with quartz countertops, sleek cabinetry with brushed nickel hardware, stainless steel appliances, new paint, and faux wood flooring.? Additionally, the property offers abundant off-street parking for tenants, including three two-car garages and one single-car garage.? With its efficient unit mix, upgraded interiors, improved building systems, ample parking, and central San Diego location, “Stonegate Manor” represents an attractive opportunity to acquire a renovated multifamily asset in one of San Diego’s established urban rental markets.?

3829 Marlborough Avenue, East San Diego

$2,800,000

260022893SD MLS ⋅ Active Status

4357-63 39th Street is a 9-unit apartment community consisting of multiple single-story structures totaling 5,080 square feet built in 1926, renovated in 2025, and situated on a 12,666 square foot lot. All the units are 1 Bedroom / 1 Bathroom and there are 9 garages, four of which are located at 4358 40th Street APN 447-202-23-00 on another 1,752 square foot lot. All units were completely remodeled in 2025. There was a new roof installed as well as stucco repair, exterior repaint, doors, and landscaping. All unit interiors feature new canned lighting, ceiling fans, window coverings and vinyl plank flooring with new baseboards. All units have new appliances and electric wall heaters powered by new sub panels. Plumbing was replaced with copper and ABS as needed. The kitchens and bathrooms feature new cabinets, fixtures, hardware, and quartz countertops.

4357 39th Street, East San Diego

$1,749,000

260022112SD MLS ⋅ Active Status

Pleased to present 4073 Chamoune Avenue, a well-maintained 5-unit multifamily investment opportunity located in San Diego’s established City Heights neighborhood. Built in 1988, the property consists of five 3-bedroom, 2-bathroom units, totaling 15 bedrooms and 10 bathrooms. The property offers seven enclosed garage parking spaces plus one additional uncovered space, providing a strong parking ratio for the asset. Additional features include alley access, electronic security gates, and an onsite laundry facility.

4073 Chamoune Ave, East San Diego

$3,100,000

260019642SD MLS ⋅ Active Status

4022 42nd Street presents an 11-unit multifamily investment opportunity in San Diego’s City Heights neighborhood. The property features six one-bedroom/one-bath units and five two-bedroom/one-bath units, including two recently added ADUs. Totaling approximately 7,354 rentable square feet on a 7,021-square-foot lot, the gated property offers on-site parking and community laundry. Conveniently located near shopping, dining, public transportation and major freeways, the property provides access to Downtown San Diego, North Park and surrounding employment centers. Buyer to verify all property information, including square footage, unit count, permits and financial data.

4022 42nd Street, East San Diego

$6,595,000

260019215SD MLS ⋅ Active Status

This is an extensively renovated (2020) and well-maintained 22-unit apartment community in the City Heights neighborhood of San Diego. This property has a fantastic unit mix: eighteen (18) 2Bdrm/2Bath with in-unit laundry and four (4) 1Bdrm/1Bath units. The property has ample onsite parking (28 spaces) and is situated in a predominantly single-family neighborhood near transit, local freeways and shopping. This represents an opportunity to acquire a fully renovated asset with strong in-place rents with additional upside in one of San Diego's best-performing submarkets. Two separate parcels (454-332-27-00 & 454-332-01-00)

3423 Marlborough Ave, East San Diego

$1,600,000

260017277SD MLS ⋅ Active Status

Attention Investors and Developers! This is an incredible opportunity to own an income property with the potential to add six additional units with approved zoning (see documents), expanding the current six-unit property to a possible twelve units. Situated on just under half an acre at the end of a quiet cul-de-sac, this property offers both privacy and convenient access to major commuter routes. With six existing units—three 2-bedroom, 1-bath units and two 1-bedroom, 1-bath units and a studio—the investment potential is outstanding. The property features two separate buildings, with four units in the main building and two units in the second building, plus plenty of parking for tenants, both in the front and back. Built in 1958, this property presents a rare chance for investors or developers to significantly increase rental income and maximize the value of the lot. Opportunities like this are hard to find—don’t miss out.

2499 Tuberose St, East San Diego

$8,995,000

260007745SD MLS ⋅ Active Status

Rare investment opportunity featuring a $49,440/month NNN master lease with House of Metamorphosis, a well-established nonprofit operator with approximately 50 years in business, delivering stable, predictable income with minimal landlord responsibility. The property consists of 26 units, each with a private bathroom, purposefully designed for supervised residential care. The 8,450 SF building offers an average unit size of approximately 325 SF, maximizing income efficiency. Situated on a 7,000 SF lot with motel zoning, the property presents limited land value contribution; however, the zoning carries significant embedded entitlement value for SRO and behavioral health uses—an increasingly scarce and difficult-to-replicate asset class in San Diego. Investors are presented with a dual-path opportunity: continue operating with a reputable, long-term tenant under a true NNN structure, or reposition the asset for alternative residential or lodging uses, leveraging the existing 26-unit configuration and flexible zoning.

4017 42nd St, East San Diego

$2,200,000

250042932SD MLS ⋅ Active Status

4062 49th Street is a 9-unit complex in City Heights with plenty of parking. The 5,190 square foot building built in 1968 is situated on a 5,739 square foot lot. There are nine 1 Bedroom / 1 Bathroom units. All units have been completely remodeled in 2025. There was a new roof installed as well as stucco repair, exterior repaint, new security doors, and water proofing of the balconies. All unit interiors feature new canned lighting, window coverings and vinyl plank flooring with new baseboards. All units have new appliances and electric wall heaters powered by new sub panels. Plumbing was replaced with copper and ABS as needed. The kitchens and bathrooms feature new cabinets, fixtures, hardware, and quartz countertops. There is an onsite laundry facility that has been expanded and has new machines. The property is located in City Heights, close to the transit and shopping off El Cajon Blvd.

4062 49th Street, East San Diego

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Based on information from California Regional Multiple Listing Service, Inc. as of . This information is for your personal, non-commercial use and may not be used for any purpose other than to identify prospective properties you may be interested in purchasing. Display of MLS data is usually deemed reliable but is NOT guaranteed accurate by the MLS. Buyers are responsible for verifying the accuracy of all information and should investigate the data themselves or retain appropriate professionals. Information from sources other than the Listing Agent may have been included in the MLS data. Unless otherwise specified in writing, Broker/Agent has not and will not verify any information obtained from other sources. The Broker/Agent providing the information contained herein may or may not have been the Listing and/or Selling Agent.